Journal: Food Science & Nutrition
Article Title: Optimization of Ultrasound Extraction of Total Anthocyanin From Berberis kaschgarica Rupr. by Response Surface Methodology and Its Antihypertensive Effect
doi: 10.1002/fsn3.4591
Figure Lengend Snippet: Serum level of (A) renin (REN); (B) angiotensin‐converting enzyme (ACE); (C) angiotensin II (Ang‐II); (D) angiotensin‐(1–7) (Ang‐(1–7)); (E) Endothelin‐1 (ET‐1); and (F) nitric oxide (NO) after 12 weeks of treatment of Wistar–Kyoto (WKY) rats and spontaneously hypertensive (SHR) rats groups. WKY group (distilled water), SHR group (distilled water), SHR + CAP group (12.5 mg/kg of captopril), SHR + BKRA‐L (50 mg/kg body of purified extract of B. kaschgarica anthocyanins), SHR + BKRA‐M (100 mg/kg of purified extract of B. kaschgarica anthocyanins), and SHR + BKRA‐H (200 mg/kg of purified extract of B. kaschgarica anthocyanins) were administered for 12 weeks by oral gavage. Each group contains 10 rats. The data are presented as mean ± standard deviation. One‐way analysis of variance (ANOVA) followed by Tukey's post hoc test, significance difference: ### p < 0.001 versus WKY group and * p < 0.05, ** p < 0.01, *** p < 0.001 versus SHR group.
Article Snippet: The REN, ACE, Ang‐II, and Ang‐(1–7) Elisa kits were purchased from Elebscience (Elabscience, Wuhan, China), while the ET‐1 and NO Elisa kits were obtained from Shanghai Elisa Biotech (Shanghai Elisa Biotech Co. Ltd. China) and Beyotime Biotechnology (Beyotime Biotechnology, Shanghai, China), respectively.
Techniques: Purification, Standard Deviation